Bone Restore with Vitamin K2 (120 Capsules)
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PINE STREET PATIENTS: We haveĀ replaced this item. |
This special formula has been designed to support healthy bone density and strength and includes 700 milligrams of elemental calcium from three different forms, along with the critically important nutrients magnesium, boron, zinc, silicon, manganese, vitamin D3, and vitamin K2 needed for healthy bones.
Note:Ā This formula is different fromĀ Bone Strength Formula.
Throughout life, cells known as osteoblasts construct bone matrix and fill it with calcium. At the same time, osteoclasts work just as busily to tear down and resorb bone. This fine balance is regulated by many factors, including systemic hormones and cytokines. Bone mass reaches its peak by the middle of the third decade of life and plateaus for about ten years, during which time bone turnover is constant, with bone formation approximately equaling bone resorption.1,2
As our bodies age, this fine balance is lost. As the relative hormone levels shift in midlife ā more drastically in women than in men ā the osteoclasts gain the upper hand and bone mass begins to dwindle. Some bone is already being lost by the time women reach menopause, but the rate of loss can increase up to tenfold during the first five years after menopause.2-4
Bone density loss is not just associated with calcium deficiency, but also with an insufficient intake of a host of other nutrients5-12Ā includingĀ magnesium11,12Ā andĀ vitamin D3.13,14Ā In order for calcium to help maintain healthy bones, adequate amounts of vitamin D3, zinc,15,16Ā magnesium,17Ā manganese,9Ā and other nutrients should be available so that calcium and phosphorus can be incorporated into the bone matrix. Additionally, many forms of calcium are not particularly well absorbed.18-20
While loss of bone mineral density is more commonly experienced by women, aging men can also have this issue.21Ā Both men and women may experience significant deficits of magnesium if they do not supplement. Bone Restore now contains 300 mg of magnesium. Magnesium is not only needed to maintain strong bones, but it is critical to promoting a healthy vascular system.22,23Ā In fact, magnesium is critical for facilitating hundreds of enzymatic reactions that our bodies require to maintain optimal health.24,25
To overcome the impediments that preclude aging adults from achieving optimal calcium status, Life Extension offers a proprietary comprehensive mineral formula calledĀ Bone RestoreĀ which has been designed to support healthy bone density and strength. Bone Restore providesĀ 700 milligramsĀ ofĀ elemental calciumĀ from three different forms, along with the critically important nutrients magnesium,17Ā boron,5,26,27Ā zinc,8,15,16Ā silicon,28-30Ā manganese9Ā and vitamin D313,14Ā needed for healthy bones.Ā
In fact, the boron in this formula, calledĀ FruiteX BĀ® OsteoBoronĀ®, is a calcium/carbohydrate/boron complex, similar to what is found in fruits and vegetables and is more bioavailable than boron citrate. Scientific research has established the beneficial effects of boron on the strength of bones and joints.5,31-34
One reason why aging people experience bone mineral density loss even though they are taking calcium supplements is that they may not beĀ absorbingĀ enough elemental calcium. Bone Restore providesĀ calciumĀ in capsule form to ensure that it breaks down fully in the digestive tract.
Calcium and other minerals are best not taken with fiber, because fiber can interfere with their absorption.35-37Ā There is evidence that calcium from supplements and dairy foods may inhibit iron absorption, although it has been very difficult to distinguish between the effects of calcium on iron absorption versus other inhibitory factors, such as phytate.38-40Ā Although current understanding of this suggests that the inhibition of calcium on absorption of iron is of short duration and the body has adaptive mechanisms.41
Calcium supplements are best taken with meals. They should always be taken with a full glass of water, juice, or other liquid to enhance solubility.42Ā If calcium-containing formulas are taken only once daily, they may be best taken in the evening.43Ā
An abundance of human clinical data reveals that vitamin K plays a critical role in maintaining healthy bone density by facilitating the transport of calcium from the bloodstream into the bone.44-48Ā Poor vitamin K status also results in increased circulating levels of undercarboxylated osteocalcin that is shown to be associated with increased bone loss in postmenopausal women.49,50
Vitamin K2Ā (menaquinones) is found in meat, eggs, and dairy products and is also made by bacteria in the human gut, which provides a certain amount of the human vitamin K requirement.51Ā Human studies show thatĀ vitamin K2Ā is up toĀ ten timesĀ more bioavailableĀ than K1. Vitamin K2 remains biologically active in the body farĀ longerĀ than K1.Ā
In recent years, two forms of vitamin K2 have been extensively researched and the findings reveal vastly improved effects compared to K1. TheĀ MK-7Ā form of K2 remains bioavailable to the human body over a sustained 24-hour period and to higher levels (seven- to eightfold) during prolonged intake.48
SoĀ itās not surprising that Bone RestoreĀ is now available withĀ vitamin K2Ā (MK-7) for those not getting their vitamin K fromĀ Super BoosterĀ orĀ Super K.
| Serving Size: 4 Capsules Servings per Container: 30 |
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| Amount per Serving: | |
| Vitamin D3 (as cholecalciferol) | 1000 IU |
| Vitamin K2 (as menaquinone-7) | 200 mcg |
| Calcium (as DimaCalĀ® dicalcium malate, TRAACSĀ® calcium bisglycinate chelate, calcium fructoborate) | 700 mg |
| Magnesium (as magnesium oxide) | 300 mg |
| Zinc (as zinc amino acid chelate) | 2 mg |
| Manganese (as manganese amino acid chelate) | 1 mg |
| Silicon [from horsetail (Equisetum arvense) extract (herb)] | 5 mg |
| Boron (calcium fructoborate as patented Fruitex BĀ® OsteoBoronĀ®) | 3 mg |
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Other Ingredients: Vegetable cellulose (capsule), vegetable stearate, maltodextrin, dicalcium phosphate, corn starch. |
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